Protein_Domain

Part:BBa_K1890052

Designed by: Lycka Kamoen, Maria Vazquez   Group: iGEM16_TU_Delft   (2016-10-12)

OmpA transmembrane domain

Usage and Biology

Outer membrane protein A (OmpA) is a native membrane protein from Escherichia coli. This biobrick contains the transmembrane domain of OmpA together with the signaling peptide and the first nine N-terminal amino acids of lipoprotein (Lpp), which is also a native protein from Escherichia coli [1]. This part is used for cell surface display of proteins. This biobrick is a subpart of BBa_K1890002. It does not exist individually.

References

[1] Francisco, J. a, Earhart, C. F., & Georgiou, G. (1992). Transport and anchoring of beta-lactamase to the external surface of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America, 89(April), 2713–2717.

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